Klinik deneyin sonuçları American Academy of Ophtalmology Nisan 2012 tarihli baskısında yayınlanmıştır.

Bu çalışmada ileri derece dış retinal dejenerasyonu bulunan kör deneklerde Argus II Retinal Protez sistemi değerlendirmiştir. 6 Haziran 2007 ve 11 Ağustos 2009 tarihleri arasında Amerika ve Avrupa da 30 denek katılmıştır. Tüm denekler minimum 6 ay olmak üzere 2.7 yıl izlenmiştir


Cover of Ophthalmology

    source: ophthalmology

Wills Eye Institut'de Uzman Optomolojist olan Julia Haller bu yayının bir özetini sunmaktadır:

Humayun MS, Dorn JD, da Cruz L, Dagnelie G, Sahel JA, Stanga PE, Cideciyan AV, Duncan JL, Eliott D, Filley E, Ho AC, Santos A, Safran AB, Arditi A, Del Priore LV, Greenberg RJ. Doheny Eye Institute, University of Southern California, Los Angeles, California. Interim Results from the International Trial of Second Sight's Visual Prosthesis. Ophthalmology Volume 119, Issue 4, 2012, Pages 779-788.

Referans Listesi:

1.            Caspi A, Roy A, Dorn JD, Greenberg RJ. Retinotopic to Spatiotopic Mapping in Blind Patients Implanted With the Argus II Retinal Prosthesis. Investigative ophthalmology & visual science. Jan 01 2017;58(1):119-127.

2.            Magill K. Nursing considerations for patients undergoing retinal prosthesis implantation: one center's experience. Insight. Q2 2017;42(2):17-21.

3.            Parmeggiani F, De Nadai K, Piovan A, Binotto A, Zamengo S, Chizzolini M. Optical coherence tomography imaging in the management of the Argus II retinal prosthesis system. Eur J Ophthalmol. Jan 19 2017;27(1):e16-e21.

4.            Tran BK, Wolfensberger TJ. Retina-Implant Interaction after 16 Months Follow-up in a Patient with an Argus II Prosthesis. Klinische Monatsblatter fur Augenheilkunde. Feb 13 2017.

5.            Barry MP, Dagnelie G. Hand-Camera Coordination Varies over Time in Users of the Argus((R)) II Retinal Prosthesis System. Frontiers in systems neuroscience. 2016;10:41.

6.            Brady-Simmons C, Van Der Biest R, Bozeman L. Miami Lighthouse for the Blind and and Visually Impaired Case Study: Vision Rehabilitation for the First Florida Resident to Receive the Argus II "Bionic Eye". Journal of Visual Impairment and Blindness. 2016;110(3):177-181.

7.            Caspi A, Dorn J, Helder JB, Katyal KD, Roy A. Eye movements as a marker for visual prosthesis spatial mapping - A feasibility study using a blind patient implanted with the Argus II retinal prosthesis. Conf Proc IEEE Eng Med Biol Soc. Aug 2016;2016:5443-5446.

8.            Castaldi E, Cicchini GM, Cinelli L, Biagi L, Rizzo S, Morrone MC. Visual BOLD Response in Late Blind Subjects with Argus II Retinal Prosthesis. PLoS Biol. Oct 2016;14(10):e1002569.

9.            da Cruz L, Dorn JD, Humayun MS, et al. Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial. Ophthalmology. Jul 19 2016.

10.         Dagnelie G, Christopher P, Arditi A, et al. Performance of real-world functional vision tasks by blind subjects improves after implantation with the Argus(R) II retinal prosthesis system. Clin Exp Ophthalmol. Aug 6 2016.

11.         Duncan JL, Richards TP, Arditi A, et al. Improvements in vision-related quality of life in blind patients implanted with the Argus II Epiretinal Prosthesis. Clinical & experimental optometry. Aug 25 2016.

12.         Geruschat DR, Dagnelie G. Restoration of vision following long-term blindness: considerations for providing rehabilitation. Journal of Visual Impairment and Blindness. 2016;January-February 2016:5-13.

13.         Geruschat DR, Richards TP, Arditi A, et al. An analysis of observer-rated functional vision in patients implanted with the Argus II Retinal Prosthesis System at three years. Clin Exp Optom. Jan 24 2016.

14.         Ghodasra DH, Chen A, Arevalo JF, et al. Worldwide Argus II implantation: recommendations to optimize patient outcomes. BMC ophthalmology. 2016;16(1):52.

15.         Gregori NZ, Davis JL, Rizzo S. Bimanual Technique for Retinal Tacking of Epiretinal Prosthesis. Retina. Jan 2016;36(1):199-202.

16.         Grewal DS, Carrasco-Zevallos OM, Gunther R, Izatt JA, Toth CA, Hahn P. Intra-operative microscope-integrated swept-source optical coherence tomography guided placement of Argus II retinal prosthesis. Acta Ophthalmol. Jun 20 2016.

17.         Luo YH, Zhong JJ, Clemo M, da Cruz L. Long-term Repeatability and Reproducibility of Phosphene Characteristics in Chronically Implanted Argus(R) II Retinal Prosthesis Subjects. American journal of ophthalmology. Aug 1 2016.

18.         Matet A, Amar N, Mohand-Said S, Sahel JA, Barale PO. Argus II retinal prosthesis implantation with scleral flap and autogenous temporalis fascia as alternative patch graft material: a 4-year follow-up. Clinical ophthalmology. 2016;10:1565-1571.

19.         Montezuma SR, Tang PH, van Kuijk FJ, Drayna P, Koozekanani DD. Implantation of the Argus II Retinal Prosthesis in an Eye With Short Axial Length. Ophthalmic surgery, lasers & imaging retina. Apr 1 2016;47(4):369-371.

20.         Ozmert E, Demirel S. Endoscope-Assisted and Controlled Argus II Epiretinal Prosthesis Implantation in Late-Stage Retinitis Pigmentosa: A Report of 2 Cases. Case Rep Ophthalmol. Sep-Dec 2016;7(3):315-324.

21.         Rachitskaya AV, Yuan A, Marino MJ, Reese J, Ehlers JP. Intraoperative OCT Imaging of the Argus II Retinal Prosthesis System. Ophthalmic surgery, lasers & imaging retina. Nov 01 2016;47(11):999-1003.

22.         Rollend DM, Rosendall PE, Wolfe KC, et al. Embedded clutter reduction and face detection algorithms for a visual prosthesis. Conf Proc IEEE Eng Med Biol Soc. Aug 2016;2016:411-414.

23.         Schimitzek H, Roessler G, Walter P. [Clinical Results after Implantation of Epiretinal Visual Prostheses]. Klinische Monatsblatter fur Augenheilkunde. Nov 2016;233(11):1227-1232.

24.         Stronks HC, Barry MP, Dagnelie G. Electrically evoked electroretinograms and pupil responses in Argus II retinal implant wearers. Doc Ophthalmol. Jan 7 2016.

25.         Cunningham S, Tjan B, Bao P, Falabella P, Weiland J. Tactile-Evoked V1 responses in Argus II Retinal Prosthesis Patients assessed with fMRI: A Case Study. J Vis. Sep 1 2015;15(12):359.

26.         Garcia S, Petrini K, Rubin GS, Da Cruz L, Nardini M. Visual and Non-Visual Navigation in Blind Patients with a Retinal Prosthesis. PLoS One. 2015;10(7):e0134369.

27.         Geruschat DR, Flax M, Tanna N, et al. FLORA: Phase I development of a functional vision assessment for prosthetic vision users. Clin Exp Optom. Feb 11 2015.

28.         Govare M, Korobelnik JF, Barale PO, et al. [Postoperative imaging after ARGUS II epiretinal prosthesis implantation in a patient with retinitis pigmentosa]. J Fr Ophtalmol. Dec 2 2015.

29.         Ho AC, Humayun MS, Dorn JD, et al. Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind. Ophthalmology. Aug 2015;122(8):1547-1554.

30.         Israelsen PE, Sadda SR, Dorn JD, Humayun MS, Olmos de Koo LC. Optomap Widefield Imaging of the Argus Ii Retinal Prosthesis in Patients with Retinitis Pigmentosa. Retin Cases Brief Rep. Dec 22 2015.

31.         Luo YH, Zhong JJ, da Cruz L. The use of Argus(R) II retinal prosthesis by blind subjects to achieve localisation and prehension of objects in 3-dimensional space. Graefes Arch Clin Exp Ophthalmol. Nov 2015;253(11):1907-1914.

32.         Seider MI, Hahn P. Argus II retinal prosthesis malrotation and repositioning with intraoperative optical coherence tomography in a posterior staphyloma. Clin Ophthalmol. 2015;9:2213-2216.

33.         Humayun MS, Da Cruz L, Dagnelie G, et al. An update on the Argus II epiretinal implant. IOVS. Vol 59682014.

34.         Kotecha A, Zhong J, Stewart D, da Cruz L. The Argus II prosthesis facilitates reaching and grasping tasks: a case series. BMC Ophthalmol. 2014;14(1):71.

35.         Rizzo S, Belting C, Cinelli L, Allegrini L. Visual field changes following implantation of the Argus II retinal prosthesis. Graefes Arch Clin Exp Ophthalmol. Nov 30 2014.

36.         Rizzo S, Belting C, Cinelli L, et al. The Argus II Retinal Prosthesis: Twelve-Month Outcomes from a Single-Study Center. Am J Ophthalmol. Feb 19 2014.

37.         Sabbah N, Authie CN, Sanda N, Mohand-Said S, Sahel JA, Safran AB. Importance of Eye Position on Spatial Localization in Blind Subjects Wearing an Argus(R) II Retinal Prosthesis. Invest Ophthalmol Vis Sci. Nov 20 2014.

38.         Vaidya A, Borgonovi E, Taylor RS, et al. The cost-effectiveness of the Argus II retinal prosthesis in Retinitis Pigmentosa patients. BMC Ophthalmol. 2014;14(1):49.

39.         Weitz AC, Behrend MR, Ahuja AK, et al. Interphase gap as a means to reduce electrical stimulation thresholds for epiretinal prostheses. J Neural Eng. Feb 2014;11(1):016007.

40.         Ahuja AK, Yeoh J, Dorn JD, et al. Factors Affecting Perceptual Threshold in Argus II Retinal Prosthesis Subjects. Transl Vis Sci Technol. Apr 2013;2(4):1.

41.         da Cruz L, Coley BF, Dorn J, et al. The Argus II epiretinal prosthesis system allows letter and word reading and long-term function in patients with profound vision loss. Br J Ophthalmol. May 2013;97(5):632-636.

42.         de Juan E, Jr., Spencer R, Barale PO, da Cruz L, Neysmith J. Extraction of retinal tacks from subjects implanted with an epiretinal visual prosthesis. Graefes Arch Clin Exp Ophthalmol. Oct 2013;251(10):2471-2476.

43.         Dorn JD, Ahuja AK, Caspi A, et al. The Detection of Motion by Blind Subjects With the Epiretinal 60-Electrode (Argus II) Retinal Prosthesis. JAMA Ophthalmol. Feb 2013;131(2):183-189.

44.         Luo YH, Davagnanam I, daCruz L. MRI brain scans in two patients with the argus II retinal prosthesis. Ophthalmology. Aug 2013;120(8):1711-1711 e1718.

45.         Stronks HC, Barry MP, Dagnelie G. Electrically elicited visual evoked potentials in Argus II retinal implant wearers. Invest Ophthalmol Vis Sci. Jun 2013;54(6):3891-3901.

46.         Barry MP, Dagnelie G. Use of the Argus II retinal prosthesis to improve visual guidance of fine hand movements. Invest Ophthalmol Vis Sci. Aug 2012;53(9):5095-5101.

47.         Dorn JD, Geruschat DR, Dagnelie G, Greenberg RJ, Group FW, Group AIS. Functional vision and quality of life of Argus(R) II Retinal Prosthesis System users as measured by the Functional Low-vision Observer Rated Assessment (FLORA). IOVS. 2012;5511(ARVO E-abstract).

48.         Humayun MS, Dorn JD, da Cruz L, et al. Interim results from the international trial of Second Sight's visual prosthesis. Ophthalmology. Apr 2012;119(4):779-788.

49.         Lauritzen TZ, Harris J, Mohand-Said S, et al. Reading visual braille with a retinal prosthesis. Front Neurosci. 2012;6:168.

50.         Perez Fornos A, Sommerhalder J, da Cruz L, et al. Temporal properties of visual perception on electrical stimulation of the retina. Invest Ophthalmol Vis Sci. May 2012;53(6):2720-2731.

51.         Weiland JD, Faraji B, Greenberg RJ, Humayun MS, Shellock FG. Assessment of MRI issues for the Argus II retinal prosthesis. Magn Reson Imaging. Apr 2012;30(3):382-389.

52.         Ahuja AK, Dorn JD, Caspi A, et al. Blind subjects implanted with the Argus II retinal prosthesis are able to improve performance in a spatial-motor task. Br J Ophthalmol. Apr 2011;95(4):539-543.

53.         Ahuja AK, Dorn JD, Caspi A, et al. Subjects implanted with the Argus II retinal prosthesis are able to improve performance in a spatial-motor task. IOVS. Vol 4442010.

54.         Christopher P, McMahon MJ, Patel U, Wei J, Greenberg R, Dorn JD. The temporal dynamics of percepts generated by the Argus II epiretinal prosthesis. Society for Neuroscience. Vol 20.32010.

55.         daCruz L, Coley B, Christopher P, et al. Patients blinded by outer retinal dystrophies are able to identify letters using the Argus II Retinal Prosthesis System. IOVS. Vol 2732010.

56.         Dagnelie G, Ahuja AK, McMahon MJ, et al. Dark-adapted flash sensitivity remains stable up to 21/2 years after Argus II implantation. IOVS. Vol 3492010.

57.         Dorn JD, Ahuja AK, Arsiero M, et al. The Argus II retinal prosthesis provides complex form vision for a subject blinded by retinitis pigmentosa. IOVS. Vol 3492010.

58.         Humayun MS, daCruz L, Dagnelie G, et al. Interim performance results from the Second Sight Argus II retinal prosthesis study. IOVS. Vol 2732010.

59.         Stanga PE, Coley B, Merlini F, Biswas S, Turner G, Greenberg R. Initial word recognition results with the Argus II Retinal Prosthesis. IOVS. Vol 1162010.

60.         Humayun MS, Dorn JD, Ahuja AK, et al. Preliminary 6 month results from the Argus II epiretinal prosthesis feasibility study. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:4566-4568.


Second Sight Medical Products, Inc. - May 15, 2017.